Research Article
Risk Factors Associated with Vancomycin-Resistant Enterococcus in Intensive Care Unit Settings in Saudi Arabia
Table 2
The risk factors that were found significantly associated with VRE on univariate analysis.
| Risk factor | Cases () | Controls () |
Adjusted odds ratio* (93% CI) | value |
| Host-related factors | | | | | | ICU admission due to multiorgan failure | 33% | 12% | 5.4% | (1.2–4.9) | 0.01 | Underlying chronic renal failure | 43% | 15% | 4.6% | (1.6–3.0) | 0.01 | Medication-related factors | | | | | | Use of antimicrobial agents in past 3 months | 69% | 20% | 11.7% | (3.6–38.1) | 0.01 | Use of pre-ICU antibiotics | 77% | 37% | 5.6% | (2.1–15.9) | 0.01 | Vancomycin | 32% | 4% | 12.7% | (1.3–119.8) | 0.03 | Metronidazole | 59% | 24% | 5.0% | (1.4–17.3) | 0.01 | Piperacillin-tazobactam | 87% | 27% | 17% | (2.9–98.4) | 0.01 | Quinolones | 54% | 18% | 5.8% | (1.5–22.1) | 0.01 | Hospital-related factors | | | | | | High risk room | 71% | 98% | 0.04% | (0.004–0.4) | 0.01 | GI contrast procedure | 17% | 2% | 12.5% | (1.3–117.6) | 0.03 | Hemodialysis | 37% | 18% | 2.9% | (1.0–8.5) | 0.05 |
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Adjusted for age, sex.
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