Research Article

Risk Factors Associated with Vancomycin-Resistant Enterococcus in Intensive Care Unit Settings in Saudi Arabia

Table 2

The risk factors that were found significantly associated with VRE on univariate analysis.

Risk factorCases
( )
Controls
( )
Adjusted odds ratio* 
(93% CI)
value

Host-related factors
 ICU admission due to multiorgan failure33%12%5.4%(1.2–4.9) 0.01
 Underlying chronic renal failure 43%15%4.6%(1.6–3.0) 0.01
Medication-related factors
 Use of antimicrobial agents in past 3 months69%20%11.7%(3.6–38.1) 0.01
 Use of pre-ICU antibiotics 77%37%5.6%(2.1–15.9) 0.01
 Vancomycin 32%4%12.7%(1.3–119.8)0.03
 Metronidazole 59%24%5.0%(1.4–17.3)0.01
 Piperacillin-tazobactam 87%27%17%(2.9–98.4) 0.01
 Quinolones54%18%5.8%(1.5–22.1)0.01
Hospital-related factors
 High risk room 71%98%0.04%(0.004–0.4) 0.01
 GI contrast procedure 17%2%12.5%(1.3–117.6)0.03
 Hemodialysis 37%18%2.9%(1.0–8.5)0.05

Adjusted for age, sex.