Predictors of Major Bleeding and Mortality in Dengue Infection: A Retrospective Observational Study in a Tertiary Care Centre in South India

Table 3

Predictors of major bleed.

Outcome	Major bleed		value
	Yes	No
Age^§	31.5 (14.3)	31.3 (13.1)	0.93
Male (n = 96)	34	62	0.30
Days of fever^§	5 (1.9)	5.14 (2.3)	0.71
Rash (n = 59)	17	42	0.498
Myalgia (n = 96)	26	70	0.96
Arthralgia (n = 20)	5	15	0.46
Vomiting (n = 112)	38	74	0.44
Loose stools (n = 32)	11	21	0.755
Abdominal pain (n = 61)	25	36	0.058
Platelet count (×10^3/μL)^§	44 (57)	65 (67)	0.059
SGOT (serum glutamic oxaloacetic transaminase) (U/L)^§	766 (2462)	254 (400)	0.036
SGPT (serum glutamic pyruvic transaminase) (U/L)^§	343 (871)	139 (192)	0.021
SOFA^a score^§	3.49 (1.6)	3.16 (1.9)	0.475
Late dengue (n = 39)	13	26	0.283
Severe dengue (n = 69)	48	21	0.0001
Secondary dengue^⋄ (n = 121)	45	76	0.014

^aSOFA, sequential organ failure assessment; ^§mean (standard deviation); value < 0.05 indicates a statistically significant association; late dengue indicates presentation after 5 days of symptom onset; ^⋄secondary dengue has both IgG and IgM antibodies positive, while primary dengue has IgM and/or NS1 antigen positive.