The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus

Table 1

Clinical and laboratory parameters and organ dysfunction.

Variables	With MODS (n = 57)	Without MODS (n = 132)	Significance
Males (n)	32	74	0.99
Age (years)	40.70 ± 14.48	37.89 ± 15.15	0.23
Duration of stay (days)	5.21 ± 2.46	4.75 ± 1.67	0.21
Duration of symptoms (days)	9.26 ± 3.75	8.96 ± 4.12	0.63
Temperature (C)	38.29 ± 0.94	38.55 ± 0.95	0.08
Pulse rate (beats/min)	101 ± 16.7	91.19 ± 13.2	0.42
Systolic blood pressure (mm·Hg)	113.61 ± 27.82	108.05 ± 14.14	0.15
Respiratory rate (breaths/min)	20.25 ± 15.19	15.17 ± 9.8	0.03
Creatinine (mg/dL)	0.90 ± 0.52	0.66 ± 0.28	0.002
Albumin (g/dL)	2.92 ± 0.95	3.53 ± 0.71	<0.001
Aspartate aminotransferase (U/L)	124.23 ± 95.36	77.08 ± 64.83	0.002
Alanine aminotransferase (U/L)	120.02 ± 81.86	73.08 ± 59.43	0.003
Alkaline phosphatase (U/L)	163.81 ± 108.46	116.30 ± 64.15	0.006
Hemoglobin (g/dL)	11.43 ± 2.16	12.21 ± 2.50	0.03
White blood cell count (×10^9/L)	9.79 ± 6.21	9.06 ± 4.75	0.38
Platelets (×10^9/L)	118.32 ± 68.97	165.32 ± 87.55	<0.001
Thrombocytopenia (n)	49	59	<0.001
Platelet distribution width (fL)	17.17 ± 1.87	17.35 ± 1.02	0.58
Platelet distribution width >16.3 (n)	55	127	0.92
Mean platelet volume (fL)	6.42 ± 1.15	6.02 ± 1.25	0.26
Mean platelet volume >7.39 fL (n)	43	74	0.01
Plateletcrit (%)	0.09 ± 0.03	0.11 ± 0.02	0.10
Plateletcrit ≤0.19% (n)	18	63	0.04
Electrocardiographic heart rate (beats/min)	95.14 ± 21.60	91.48 ± 14.09	0.39
Meningitis (n)	10	3	<0.001
Acute respiratory distress syndrome (n)	2	1	0.16
qSOFA scores (mean ± SD)	0.65 ± 0.64	0.39 ± 0.54	0.01
Score 0 (n)	84	25	0.02
Score 1 (n)	44	27
Score 2 (n)	4	5
Acute kidney injury (n)	15	4	<0.001
Shock (n)	6	3	0.014
Pneumonitis (n)	32	3	<0.001
Hepatitis (n)	12	10	0.08
Mortality (n)	2	1	0.16