Efficacy of Colchicine and Budesonide in Improvement Outcomes of Patients with Coronavirus Infection 2019 in Damascus, Syria: A Randomized Control Trial

Table 2

Admission criteria, laboratories, and additional supportive treatments.

Laboratory characteristics		Supportive	Colchicine	Budesonide	value
Admission criteria	sat ≤ 93% + 1 condition	4	4	0	0.11
	sat ≤ 93% + 2 conditions	9	4	6	0.69
	sat ≤ 93% + 3 conditions	8	6	8	0.70
WBCs (white blood cells)	≤10th/ml	8	7	7	0.70
	10–20th/ml	13	7	4	0.21
	≥20th/ml	0	0	3	0.01
Lymphocytes	≤5%	9	1	5	0.05
	5–10%	6	6	4	0.36
	10–20%	6	6	4	0.62
	≥20%	0	1	1	0.46
HB (hemoglobin)	≤10 g/dl	6	4	1	0.26
	10–13 g/dl	9	5	10	0.12
	≥13 g/dl	6	5	3	0.87
PLT (platelets)	<150th/ml	5	1	3	0.40
	≥150th/ml	16	13	11	0.40
Ur (urea)	≤45 mg/dl	8	6	5	0.02
	45–100 mg/dl	6	5	5	0.87
	≥100 mg/dl	6	3	5	0.74
Cr (creatinine)	0.5–1.2 mg/dl	11	8	8	0.94
	1.2–2 mg/dl	4	3	2	0.83
	2–3 mg/dl	3	2	3	0.83
	≥3 mg/dl	3	1	1	0.78
ALT (alanine aminotransferase)	≤41 mg/dl	15	9	9	0.87
	41–100 mg/dl	5	5	5	0.87
	≥100 mg/dl	1	0	0	0.51
AST (aspartate aminotransferase)	≤38 mg/dl	11	5	6	0.61
	38–100 mg/dl	8	9	7	0.31
	≥100 mg/dl	2	0	1	0.44
CK (creatine kinase)	≤170 mg/dl	17	9	12	0.35
	170–500 mg/dl	4	4	0	0.11
	≥500 mg/dl	0	1	2	0.27
LDH (lactate dehydrogenase)	≤480 mg/dl	5	0	1	0.08
	480–1000 mg/dl	9	8	10	0.25
	≥1000 mg/dl	7	6	3	0.48
PT (prothrombin time)	<60%	4	0	3	0.19
	≥60%	17	14	11	0.19
INR (international normalized ratio)	≤1.2	16	12	10	0.65
	>1.2	5	2	4	0.65
CRP (C-reactive protein)	≤0.5	ـــــ	ـــــ	ـــــ	ـــــ
	0.5–10	9	9	5	0.28
	10–20	7	4	5	0.91
	≥20	5	1	4	0.08
Pro-CT (procalcitonin)	<0.1	8	5	5	0.27
	0.1–0.5	8	7	5	0.70
	≥0.5	5	2	4	0.65
D-dimer	<1000	12	8	4	0.19
	≥1000	9	6	10	0.19
Crcl (creatinine clearance)	≥90	7	5	5	0.96
	90–60	4	5	4	0.53
	60–30	6	3	3	0.84
	<30	4	1	2	0.17
Antibiotic	Azithro	3	3	1	0.36
	Azithro + ceftriaxone	11	7	6	0.85
	Levofloxacin	6	4	6	0.63
	Others	1	0	1	0.62
Padua score	<4	ـــــ	ـــــ	ـــــ	ـــــ
	≥4	21	14	14	1
Anticoagulants	Enoxaparin 40 mg/d	9	5	6	0.90
	Apixaban 2.5 mg/twice/d	3	3	1	0.56
	Apixaban 5 mg/twice/d	9	6	7	0.93
Other drugs		10	6	4	0.52
Complications of COVID-19		6	4	6	0.62