Research Article

3D Molecular Modelling Study of the H7N9 RNA-Dependent RNA Polymerase as an Emerging Pharmacological Target

Figure 1

The homology modelling and docking experiment for the establishment of the 3D structure of the H7N9 RdRp structure. Top: the components that were used to construct the 3D complex model of the H7N9 RdRp. A, B, C, D, F, and H are crystal structures, whereas E and G (pointed by the grey arrows) have been built using homology-modelling techniques. Bottom: the full complex structure of the H7N9 RdRp as established by the docking experiment. The PA domain is shown in green, the PB1 in blue, and the pB2 in red ribbon representation.
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