Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers

Figure 1

(a) Mean LDL-c concentration related to increasing extent of gingival plaque (in tertils) without and with statin use. ANOVA: statins 𝑃<0.001, plaque tertils 𝑃=0.475, interaction 𝑃<0.001. (b) Mean LDL-c dependent on severity of attachment loss (mean CAL tertils) without and with statin use. ANOVA: statins 𝑃=0.003, CAL tertils 𝑃=0.366, interaction statins *CAL 𝑃=0.002. Lowest periodontal tertil—white columns, 2nd tertil—dark columns, 3rd tertil—hatched columns.

(a)

(b)