Research Article

Endocrine Alterations Are the Main Determinants of Cardiac Remodelling in Restrictive Anorexia Nervosa

Table 2

Comparison between patients with adequate and inadequate left ventricular mass.

Adequate LVM ( 𝑛 = 1 8 )Inadequate LVM ( 𝑛 = 7 ) 𝑃 =

Age (years) 2 3 ± 6 2 6 ± 1 4 0.4
HR (bpm) 6 0 ± 1 1 5 4 ± 1 0 0.2
SBP (mm Hg) 9 3 ± 8 9 0 ± 7 0.4
DBP (mm Hg) 6 2 ± 8 6 4 ± 5 0.7
BMI 1 5 . 3 ± 1 . 6 1 3 . 9 ± 2 . 0 0.08
Albumin (g/dL) 4 . 5 ± 0 . 5 4 . 1 ± 0 . 8 0.2
Hemoglobin (g/dL) 1 2 . 3 ± 2 1 1 . 7 ± 3 0.4
GH (ng/mL) 7 . 1 ± 6 . 5 2 3 . 9 ± 2 5 0.03*
IGF-1 (ng/mL) 1 3 6 . 4 ± 5 0 . 9 1 0 3 . 6 ± 5 7 0.2
logIGF1/GH 1 . 4 ± 0 . 5 0 . 8 ± 0 . 7 0.02*
FT3 (pg/mL) 2 . 1 ± 0 . 3 1 . 3 ± 0 . 3 <0.001*
FT4 (ng/dL) 0 . 9 ± 0 . 1 0 . 9 ± 0 . 2 0.7
TSH ( 𝜇 U/mL) 2 . 1 ± 0 . 5 1 . 9 ± 0 . 4 0.6
Cortisol (ng/mL) 1 6 1 ± 3 2 1 8 9 ± 4 4 0.1
FMD (%) 1 4 . 0 ± 5 . 8 1 3 . 5 ± 2 . 5 0.8
Mean 24-hour HR (bpm) 7 1 ± 8 6 4 ± 6 0.07
Age at onset (years) 1 5 . 3 ± 2 . 0 1 5 . 2 ± 1 . 6 0.8
Disease duration (years) 7 . 7 ± 5 . 6 1 1 . 0 ± 1 2 . 8 0.4

Note. See Table 1. 𝑃 < 0 . 0 5 at unpaired t-test.