Table of Contents
ISRN Cardiology
Volume 2011, Article ID 176834, 7 pages
Review Article

Novel Pharmacological Interventions to Maintain Sinus Rhythm after DC Cardioversion

The Department of Cardiology, University Hospital of Wales, Heath Park, Cardiff CF14 4XN Wales, UK

Received 27 March 2011; Accepted 15 May 2011

Academic Editors: O. D. Pedersen and W.-C. Yu

Copyright © 2011 D. E. Thomas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Despite the availability of potentially curative interventions for atrial fibrillation, there remains an important role for conventional anti-arrhythmic therapy and anti-coagulation combined with direct current cardioversion. Unfortunately, the latter approach is disturbed by high recurrence rates of atrial fibrillation. In recent years, several adjunctive therapies have emerged which may facilitate the maintenance of sinus rhythm. These novel therapies and their potential mechanisms of action are reviewed in this article.