Table of Contents
ISRN Neurology
Volume 2011, Article ID 219427, 9 pages
Review Article

Apathy and Anhedonia in Parkinson's Disease

Department of Neurology, Dokkyo Medical University, 880-Kitakobayashi, Mibu, Tochigi 321-0293, Japan

Received 3 March 2011; Accepted 18 April 2011

Academic Editor: A. Lagares

Copyright © 2011 Yoshiaki Kaji and Koichi Hirata. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Depression, apathy, and anhedonia are often comorbid in patients with Parkinson's disease. Since the morbid states of apathy and anhedonia are complicated, these symptoms are often difficult to diagnose. Several therapeutic methods for apathy and anhedonia are considered effective. However, the validity of these methods has not been established. Similar to depression, apathy and anhedonia clearly affect the quality of life of patients and their families. Therefore, accurate diagnoses of morbid states in the early stage of the disease and corresponding appropriate treatments should be given high priority.