“Abscopal” Effect of Radiation Therapy Combined with Immune-Therapy Using IFN-γ Gene Transfected Syngeneic Tumor Cells, in Rats with Bilateral Implanted N29 Tumors
Figure 2
The left diagrams show the tumor volume of the left-lateral untreated bystander tumors, and the right diagrams show the tumor volume of the right-lateral radiation-treated tumors. The solid lines show the curve fitted by an exponential growth model for , that is, 30 days. In the left diagram of untreated tumors, the asterisk (*) indicates the occasion of radiation treatment of the corresponding right-lateral tumors. In the right diagram for the right lateral treated tumors the thick arrow at “RT exposed” indicates the four radiation treatment fractions. The occasions of immunizations are indicated with double arrows.
(a) Tumor volumes at each time of measurement in all tumors of the controls in the series-B
(b) Tumor volumes at each time of measurement in all tumors of the IMU- treated rats in the series-B
(c) Tumor volumes at each time of measurement in all tumors of the RT group in the series-B
(d) Tumor volumes at each time of measurement in all tumors of the RT+ IMU-IFNγ group in the series-B
