Research Article
Preparation of Fluconazole -Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation
Table 1
Composition of various polymers in different formulations per ring.
| | Formulation | HPMC-K4M (%w/v) | EC (%w/v) | Dibutyl phthalate (%v/w) | Fluconazole β-CD (mg) |
| | F-1 | 1.0 | 4.0 | 10.0 | 300 | | F-2 | 1.0 | 5.0 | 10.0 | 300 | | F-3 | 1.0 | 6.0 | 10.0 | 300 | | F-4 | 1.5 | 4.0 | 10.0 | 300 | | F-5 | 1.5 | 5.0 | 10.0 | 300 | | F-6 | 1.5 | 6.0 | 10.0 | 300 | | F-7 | 2.0 | 4.0 | 10.0 | 300 | | F-8 | 2.0 | 5.0 | 10.0 | 300 | | F-9 | 2.0 | 6.0 | 10.0 | 300 |
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12 mL of the cast solution was poured into petri dish to prepare circular cast film.
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