International Scholarly Research Notices / 2011 / Article / Tab 2

Research Article

Preparation of Fluconazole 𝜷 -Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation

Table 2

Physicochemical evaluation of different formulations.

FormulationThickness (mm)Weight uniformity (mg)Moisture loss (%)Moisture absorption (%)Folding enduranceDrug content (%)

F-10.16 ± 0.00217.55 ± 0.1077.84 ± 0.0154.78 ± 0.22274 ± 6.68189.51 ± 4.568
F-20.16 ± 0.00116.37 ± 0.1098.54 ± 0.0845.35 ± 0.15585 ± 5.84791.16 ± 6.593
F-30.16 ± 0.00418.35 ± 0.0459.68 ± 0.0456.28 ± 0.16991 ± 6.65690.26 ± 2.658
F-40.16 ± 0.00515.89 ± 0.0286.29 ± 0.1097.84 ± 0.18468 ± 5.51785.65 ± 9.657
F-50.17 ± 0.00316.89 ± 0.1167.57 ± 0.2278.94 ± 0.16774 ± 8.59489.51 ± 7.215
F-60.16 ± 0.00418.48 ± 0.1538.52 ± 0.0249.84 ± 0.14885 ± 6.84995.21 ± 4.123
F-70.16 ± 0.00615.98 ± 0.1177.94 ± 0.0877.51 ± 0.15385 ± 6.59888.32 ± 6.597
F-80.16 ± 0.00516.84 ± 0.1578.54 ± 0.2478.15 ± 0.04891 ± 2.95595.84 ± 5.648
F-90.17 ± 0.00517.97 ± 0.1489.19 ± 0.0289.84 ± 0.05898 ± 5.62197.26 ± 2.255

All values were expressed as mean ± S.D; number of trials ( 𝑛 ) = 5 .