Table of Contents
ISRN Pharmaceutics
Volume 2011, Article ID 246162, 5 pages
http://dx.doi.org/10.5402/2011/246162
Research Article

Preparation and Characterisation of Highly Loaded Fluorescent Chitosan Nanoparticles

Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur Campus, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia

Received 8 August 2011; Accepted 27 September 2011

Academic Editors: Y. Murata and B. Nigovic

Copyright © 2011 Haliza Katas and Chan Mui Wen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Panyam and V. Labhasetwar, “Biodegradable nanoparticles for drug and gene delivery to cells and tissue,” Advanced Drug Delivery Reviews, vol. 55, no. 3, pp. 329–347, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. K. Kurita, “Chitin and chitosan: functional biopolymers from marine crustaceans,” Marine Biotechnology, vol. 8, no. 3, pp. 203–226, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. Z. Jiayin and W. Jianmin, “Preparation and characterization of the fluorescent chitosan nanoparticle probe,” Chinese Journal of Analytical Chemistry, vol. 34, no. 11, pp. 1555–1559, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. S. A. Agnihotri, N. N. Mallikarjuna, and T. M. Aminabhavi, “Recent advances on chitosan-based micro- and nanoparticles in drug delivery,” Journal of Controlled Release, vol. 100, no. 1, pp. 5–28, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. V. R. Sinha, A. K. Singla, S. Wadhawan et al., “Chitosan microspheres as a potential carrier for drugs,” International Journal of Pharmaceutics, vol. 274, no. 1-2, pp. 1–33, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. Y. Chen, V. J. Mohanraj, F. Wang, and H. A. E. Benson, “Designing chitosan-dextran sulfate nanoparticles using charge ratios,” AAPS PharmSciTech, vol. 8, no. 4, pp. 131–139, 2007. View at Google Scholar · View at Scopus
  7. S. De and D. Robinson, “Polymer relationships during preparation of chitosan-alginate and poly-l-lysine-alginate nanospheres,” Journal of Controlled Release, vol. 89, no. 1, pp. 101–112, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. F. Wang, Micro and nanoparticles for site-specific drug delivery in the skin, M.S. thesis, Curtin University of Technology, Perth, Australia, 2005.
  9. C. He, Y. Hu, L. Yin, C. Tang, and C. Yin, “Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles,” Biomaterials, vol. 31, no. 13, pp. 3657–3666, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. S. Mansouri, Y. Cuie, F. Winnik et al., “Characterization of folate-chitosan-DNA nanoparticles for gene therapy,” Biomaterials, vol. 27, no. 9, pp. 2060–2065, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. Y. L. Wang and M. B. Goren, “Differential and sequential delivery of fluorescent lysosomal probes into phagosomes in mouse peritoneal macrophages,” Journal of Cell Biology, vol. 104, no. 6, pp. 1749–1754, 1987. View at Google Scholar · View at Scopus
  12. J. Keifer, D. Vyas, and J. C. Houk, “Sulforhodamine labeling of neural circuits engaged in motor pattern generation in the in vitro turtle brainstem-cerebellum,” Journal of Neuroscience, vol. 12, no. 8, pp. 3187–3199, 1992. View at Google Scholar · View at Scopus
  13. M. J. McLaren, G. Inana, and C. Y. Li, “Double fluorescent vital assay of phagocytosis by cultured retinal pigment epithelial cells,” Investigative Ophthalmology & Visual Science, vol. 34, no. 2, pp. 317–326, 1993. View at Google Scholar · View at Scopus
  14. O. Kjaerulff, I. Barajon, and O. Kiehn, “Sulphorhodamine-labelled cells in the neonatal rat spinal cord following chemically induced locomotor activity in vitro,” Journal of Physiology, vol. 478, part 2, pp. 265–273, 1994. View at Google Scholar · View at Scopus
  15. N. Takahashi, T. Kishimoto, T. Nemoto, T. Kadowaki, and H. Kasai, “Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet,” Science, vol. 297, no. 5585, pp. 1349–1352, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. J. S. Suh, J. Y. Lee, Y. S. Choi et al., “Efficient labeling of mesenchymal stem cells using cell permeable magnetic nanoparticles,” Biochemical and Biophysical Research Communications, vol. 379, no. 3, pp. 669–675, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  17. Y. Chen, V. J. Mohanraj, and J. E. Parkin, “Chitosan-dextran sulfate nanoparticles for delivery of an anti-angiogenesis peptide,” International Journal of Peptide Research and Therapeutics, vol. 10, no. 5-6, pp. 621–629, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. Sigma-Aldrich, Product Information. Sulforhodamine 101 Acid Chloride.