Table of Contents
ISRN Oncology
Volume 2011, Article ID 247385, 5 pages
http://dx.doi.org/10.5402/2011/247385
Research Article

Role and Efficacy of Intraoperative Evaluation of Resection Adequacy in Conservative Breast Surgery

1Dipartimento di Patologia, Ospedale San Giovanni Antica Sede, A.S.O. San Giovanni Battista Molinette, Via Cavour 31 10126 Torino, Italy
2Dipartimento di Radiologia, Ospedale San Giovanni Antica Sede, A.S.O. San Giovanni Battista Molinette, 10126 Torino, Italy
3Centro di Riferimento per l'Epidemiologia e la Prevenzione Oncologica in Piemonte (CPO Piemonte), 10126 Turin, Italy
4Dipartimento di Chirurgia del Seno, Ospedale San Giovanni Antica Sede, A.S.O. San Giovanni Battista Molinette, 10126 Torino, Italy

Received 7 February 2011; Accepted 6 March 2011

Academic Editor: M. Al-Sarraf

Copyright © 2011 G. Canavese et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In the present study we considered the histology of 51 patients who have undergone breast conservative surgery and the related 54 re-excisions that were performed in the same surgical procedure or in delayed procedures, in order to evaluate the role of intraoperative re-excisions in completing tumor removal. In 13% of the cases the re excision obtained the resection of the target lesion. In this study, the occurrence of residual neoplastic lesions in intraoperative re-excisions (24%) is lower than in delayed re-excisions (62%; 𝑃 = . 0 3 ). The residual lesions that we could find with definitive histology of re excision specimens are related with lesions with ill defined profile. In 77% of the cases of re excision with tumoral residual the lesion was close to the new resection margin, thus the re-excisions couldn't achieve an adequate ablation of the neoplasm. Invasive or preinvasive nature of the main lesion resected for each case and the approach to the evaluation of the first resection specimen adequacy (surgical or radiological) don't affect the rate of tumoral residual in intraoperative re-excisions. In conclusion, our data are consistent with a low efficacy of intraoperative re excision in obtaining a complete removal of the tumor; intraoperative radiologic evaluation of the first resection specimen is however imperative in defining the effective removal of the target lesion.