Table of Contents
ISRN Pharmaceutics
Volume 2011, Article ID 260537, 5 pages
Research Article

Water-soluble Fraction of Abelmoschus esculentus L Interacts with Glucose and Metformin Hydrochloride and Alters Their Absorption Kinetics after Coadministration in Rats

1Department of Pharmacy, Southeast University, Dhaka 1213, Bangladesh
2Department of Pharmacy, University of Rajshahi, Rajshahi 6205, Bangladesh
3Department of Pharmacy, University of Asia Pacific, Dhaka 1209, Bangladesh

Received 8 June 2011; Accepted 10 July 2011

Academic Editors: Y. Murata and T. Pongjanyakul

Copyright © 2011 Hajera Khatun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. C. Bailey, “Diabetes,” The Indian Journal of Experimental Biology, vol. 37, pp. 190–192, 2002. View at Google Scholar
  2. Media Center, World Health Organization (WHO),
  3. A. Tabatabai and S. Li, “Dietary fiber and type 2 diabetes,” Clinical Excellence for Nurse Practitioners, vol. 4, no. 5, pp. 272–276, 2000. View at Google Scholar
  4. U.S. National Library of Medicine,
  5. Remington: The Science and Practice of Pharmacy, Lippincott Williams and Wilkins, 20th edition, 2006.
  6. H. Gin, M. B. Orgerie, and J. Aubertin, “The influence of Guar gum on absorption of metformin from the gut in healthy volunteers,” Hormone and Metabolic Research, vol. 21, no. 2, pp. 81–83, 1989. View at Google Scholar
  7. M. Begum, S. Ravishankar, R. V. Shailaja, M. D. Kumar, and S. H. Shetty, “Evaluation of certain storage conditions for okra (Abelmoscus esculentus L. Moench) seeds against potential fungal pathogens,” International Journal of Agriculture and Biology, vol. 4, pp. 550–554, 2005. View at Google Scholar
  8. The National Academies Press, “Okra,” in Lost Crops of Africa: Volume II: Vegetables, 2006. View at Google Scholar
  9. M. S. Alam and G. M. A. Khan, “Chemical analysis of okra bast fiber (Abelmoschus esculentus) and its physico-chemical properties,” Journal of Textile and Apparel Technology and Management, vol. 5, no. 4, 2007. View at Google Scholar
  10. “Diabetes Guide: Treatment and care,” medicine/.
  11. M. H. Khatun, M. A. Rahman, M. Biswas, and M. A. Islam, “In vitro study of the effects of viscous soluble dietary fibers of Abelmoschus esculentus L in lowering intestinal glucose absorption,” Bangladesh Pharmaceutical Journal, vol. 13, no. 2, pp. 35–40, 2010. View at Google Scholar
  12. W. H. Yokoyama, C. A. Hudson, B. E. Knuckles et al., “Effect of barley beta-glucan in durum wheat pasta on human glycemic response,” Cereal Chemistry, vol. 74, no. 3, pp. 293–296, 1997. View at Google Scholar
  13. S. Ou, K. C. Kwok, Y. Li, and L. Fu, “In vitro study of possible role of dietary fiber in lowering postprandial serum glucose,” Journal of Agricultural and Food Chemistry, vol. 49, no. 2, pp. 1026–1029, 2001. View at Publisher · View at Google Scholar
  14. L. Lafrance, R. Rabasa, D. Poisson, F. Ducros, and J. L. Chiassion, “Effects of different glycemic index food and dietary fiber intake on glycemic control in type I diabetic patients on intensive insulin therapy,” Diabetic Medicine, vol. 15, pp. 972–978, 1998. View at Google Scholar
  15. I. Torsdottir, M. Alpsten, G. Holm, A. M. Sandberg, and J. Tolli, “A small dose of soluble alginate fiber affects postprandial glycemia and gastric emptying in humans with diabetes,” Journal of Nutrition, vol. 121, no. 6, pp. 795–799, 1991. View at Google Scholar
  16. I. M. Liu, S. S. Liou, T. W. Lan, F. L. Hsu, and J. T. Cheng, “Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats,” Planta Medica, vol. 71, no. 7, pp. 617–621, 2005. View at Publisher · View at Google Scholar · View at PubMed
  17. H. N. Trinh, N. N. Quynh, T. V. Anh, and V. P. Nguyen, “Hypolipidemic effect of extracts from Abelmoschus esculentus L.—Malvaceae on tyloxapol-induced hyperlipidemia in mice,” in Proceedings of the 13th International Electronic Conference on Synthetic Organic Chemistry (ECSOC '09), 2009.