Table of Contents
ISRN Organic Chemistry
Volume 2011, Article ID 273136, 5 pages
Research Article

Ammonium Trifluoroacetate-Mediated Synthesis of 3,4-dihydropyrimidin-2(1H)-ones

1Pachaiyappa's College, University of Madras, Aminjikarai, Chennai 600 029, India
2HEM Laboratories, National University of Singapore, Singapore
3King Saud University, Riyadh 11451, Saudi Arabia

Received 9 August 2011; Accepted 4 September 2011

Academic Editors: A. Iuliano and G. Li

Copyright © 2011 Chandran Raju et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A simple and economic synthesis of 3,4-dihydropyrimidin-2(1H)-ones using ammonium trifluoroacetate as catalyst and as solid support is accomplished. Easy workup procedure for the synthesis of title compounds is well arrived at and is well documented.