Clinical Study
Safety and Immunogenicity of a Human Papillomavirus Peptide Vaccine (CIGB-228) in Women with High-Grade Cervical Intraepithelial Neoplasia: First-in-Human, Proof-of-Concept Trial
Table 1
Results of detection of HPV16 correlated with clinical and immune response.
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Note: All patients were positive for HLA-A2. Initial histology was by cervical biopsy prior to the study. End histology was by LEEP at termination of the study (90 days after the first vaccine administration). Abbreviations CIN II-III: cervical intraepithelial neoplasia, grade II or III. CR: complete response; PR: partial response; SD: stable disease. |