Table of Contents
ISRN Gastroenterology
Volume 2011, Article ID 308727, 8 pages
http://dx.doi.org/10.5402/2011/308727
Research Article

Helicobacter pylori Induces Disturbances in Gastric Mucosal Akt Activation through Inducible Nitric Oxide Synthase-Dependent S-Nitrosylation: Effect of Ghrelin

Research Center, C875 University of Medicine and Dentistry of New Jersey Dental School, 110 Bergen Street, P.O. Box 1709, Newark, NJ 07103-2400, USA

Received 21 September 2010; Accepted 21 October 2010

Academic Editor: J.-P. Buts

Copyright © 2011 Bronislaw L. SLomiany and Amalia Slomiany. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Slomiany, and Slomiany, “Role of ghrelin-induced cSrc activation in modulation of gastric mucosal inflammatory responses to Helicobacter pylori,” Inflammopharmacology, vol. 19, no. 4, pp. 197–204, 2011. View at Publisher · View at Google Scholar
  • Slomiany, and Slomiany, “Ghrelin suppression of Helicobacter pylori-induced S-nitrosylation- dependent Akt inactivation exerts modulatory influence on gastric mucin synthesis,” Inflammopharmacology, vol. 19, no. 2, pp. 89–97, 2011. View at Publisher · View at Google Scholar
  • Bronislaw L. Slomiany, and Amalia Slomiany, “Role of constitutive nitric oxide synthase in regulation of <i>Helicobacter pylori</i>-induced gastric mucosal cyclooxygenase-2 ac-tivation through S-nitrosylation: mechanism of ghrelin action,” Open Journal of Gastroenterology, vol. 01, no. 02, pp. 13–22, 2011. View at Publisher · View at Google Scholar
  • B. L. Slomiany, and A. Slomiany, “Involvement of p38 MAPK-dependent activator protein (AP-1) activation in modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin,” Inflammopharmacology, vol. 21, no. 1, pp. 67–78, 2012. View at Publisher · View at Google Scholar
  • Caleb L. Grey, and John P. Chang, “Ghrelin-induced growth hormone release from goldfish pituitary cells is nitric oxide dependent,” General and Comparative Endocrinology, vol. 179, no. 2, pp. 152–158, 2012. View at Publisher · View at Google Scholar
  • Petra Hudler, “Genetic Aspects of Gastric Cancer Instability,” The Scientific World Journal, vol. 2012, pp. 1–10, 2012. View at Publisher · View at Google Scholar
  • Bronislaw L. Slomiany, and Amalia Slomiany, “Modulation of gastric mucosal inflammatory responses to <i>Helicobacter pylori</i> by ghrelin: Role of cNOS-dependent IKK-<i>β</i> S-nitrosylation in the regulation of COX-2 activation,” American Journal of Molecular Biology, vol. 02, no. 02, pp. 113–123, 2012. View at Publisher · View at Google Scholar
  • B. L. Slomiany, and A. Slomiany, “Role of ghrelin-induced phosphatidylinositol 3-kinase activation in modulation of gastric mucosal inflammatory responses to Helicobacter pylori,” Inflammopharmacology, 2013. View at Publisher · View at Google Scholar
  • B. L. Slomiany, and A. Slomiany, “Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK-mediated activation of IKK-β and cPLA2: modulatory effect of ghrelin,” Inflammopharmacology, 2013. View at Publisher · View at Google Scholar
  • Caleb L. Grey, and John P. Chang, “Nitric oxide signaling in ghrelin-induced LH release from goldfish pituitary cells,” General and Comparative Endocrinology, vol. 183, pp. 7–13, 2013. View at Publisher · View at Google Scholar
  • B. L. Slomiany, and A. Slomiany, “Modulation of gastric mucosal inflammatory responses to Helicobacter pylori via ghrelin-induced protein kinase Cδ tyrosine phosphorylation,” Inflammopharmacology, 2014. View at Publisher · View at Google Scholar
  • Olga Gorelenkova Miller, and John J. Mieyal, “Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases,” Archives of Toxicology, 2015. View at Publisher · View at Google Scholar
  • Zhen Yang, Zhijun Luo, Nonghua Lu, Chuan Xie, Wenting Xu, Gongmeizi Liu, Ximei Cao, Wei Li, Jiang Chen, Yin Zhu, and Shiwen Luo, “Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway.,” Oncotarget, vol. 6, no. 31, pp. 31916–26, 2015. View at Publisher · View at Google Scholar
  • Nagehan Can, Onur Catak, Burak Turgut, Tamer Demir, Nevin Ilhan, Tuncay Kuloglu, and Ibrahim Hanifi Ozercan, “Neuroprotective and antioxidant effects of ghrelin in an experimental glaucoma model.,” Drug design, development and therapy, vol. 9, pp. 2819–29, 2015. View at Publisher · View at Google Scholar
  • Natale Figura, Luigi Marano, Elena Moretti, and Antonio Ponzetto, “Helicobacter pylori infection and gastric carcinoma: Not all the strains and patients are alike.,” World journal of gastrointestinal oncology, vol. 8, no. 1, pp. 40–54, 2016. View at Publisher · View at Google Scholar
  • B. L. Slomiany, and A. Slomiany, “Role of LPS-elicited signaling in triggering gastric mucosal inflammatory responses to H. pylori: modulatory effect of ghrelin,” Inflammopharmacology, 2017. View at Publisher · View at Google Scholar