Table of Contents
ISRN Dermatology
Volume 2011, Article ID 342909, 4 pages
Case Report

Xanthoma Disseminatum In a Pair of Blind, Deaf Male Twins

1Western University of Health Sciences, 309 East Second Street, Pomona, CA 91766, USA
2Department of Dermatology, University of Southern California, Los Angeles, CA 90033, USA
3University of California, Los Angeles, CA 90095, USA

Received 11 January 2011; Accepted 10 February 2011

Academic Editors: E. Fonseca, H. Starz, and A. Tosca

Copyright © 2011 Naveed Natanzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Xanthoma disseminatum (XD) is a rare normolipemic histiocytic disorder of non-Langerhans cell origin characterized by erythematous to tan/brown papules in flexor surfaces. Considered a generally benign, chronic disease of unknown etiology, XD typically affects the skin, mucous membranes, and less commonly, other organs. To date, there has been no typical or consistent inheritance pattern described, nor has it ever been considered as a component of any known syndrome. We describe, for the first time, two cases of XD in a pair of blind and deaf twin brothers.