Table of Contents
ISRN Dermatology
Volume 2011, Article ID 346754, 4 pages
Case Report

Photodynamic Therapy for Basal Cell Carcinoma in Recessive Dystrophic Epidermolysis Bullosa

1Department of Dermatology, The Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia
2Department of Medicine, The University of Melbourne, Parkville, VIC 3050, Australia
3Department of Dermatology, St. Vincent's Hospital, Fitzroy, VIC 3065, Australia
4Skin and Cancer Foundation, 80 Drummond Street, Carlton, VIC 3053, Australia

Received 19 February 2011; Accepted 24 March 2011

Academic Editor: C. Ferrándiz

Copyright © 2011 Myn Wee Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 22-year-old male with recessive dystrophic epidermolysis bullosa with a large superficial and nodular basal cell carcinoma on his right forehead was treated with photodynamic therapy. The treatment was well tolerated, and the site healed well. Patients with epidermolysis bullosa are at increased risk of developing skin cancers, particularly squamous cell carcinomas. However, basal cell carcinomas are rare in recessive dystrophic epidermolysis bullosa. As patients with epidermolysis bullosa have recurrent blistering and poor wound healing, surgery may not be the optimal choice in treating skin cancers. We present this case to highlight that photodynamic therapy may be a helpful and safe technique in the treatment of superficial skin cancers in patients with epidermolysis bullosa, as an alternative to more radical methods.