The Effect of Multidisciplinary Lifestyle Intervention on the Pre- and Postprandial Plasma Gut Peptide Concentrations in Children with Obesity

Table 2

Clinical and physiological parameters of the subjects with complete data (𝑁=36).

Variables	Baseline (T1)	After (T2)	P Value*
BMI-SDS	4.2±0.7	4.0±0.9	.003
HOMA-IR	4.2±2.5	4.1±3.0	NS
Glucose (fasting) (mmol/L)	5.2±0.4	5.3±0.4	NS
Glucose AUC (165 min × mmol/L)	905±67	896±86	NS
Insulin (fasting) (mU/L)	18.0±10.7	17.4±12.5	NS
Insulin AUC (165 min × U/L)^†	10.3±6.1	11.0±8.0	NS
Ghrelin (fasting) (pg/mL)	612±143	641±144	NS
Ghrelin AUC (165 min × pg/L)^†	92.3±18.3	97.9±18.2	.006
PYY (fasting) (pg/mL)	90.2±34.6	95.5±32.8	NS
PYY AUC (165 min × pg/L)	16.3±4.6	15.3±5.0	NS
GLP-1 (fasting) (pM/L)	2.6±0.9	2.5±0.9	NS
GLP-1 AUC (165 min × pM/L)	567±192	552±197	NS

* P value T2 versus T1 (paired t-test).