Table of Contents
ISRN Pediatrics
Volume 2011 (2011), Article ID 380283, 7 pages
http://dx.doi.org/10.5402/2011/380283
Clinical Study

The Use of Dexamethasone in Bacterial Meningitis in Children and Adults: A Retrospective Analysis

Pediatric Critical Care Medicine Department, Universitair Ziekenhuis Brussel, 1090 Brussels, Belgium

Received 29 September 2011; Accepted 4 November 2011

Academic Editors: M. Adhikari and S. A. Sarker

Copyright © 2011 An-Sophie Cornelis and Said Hachimi-Idrissi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. M. Scheld, U. Koedel, B. Nathan, and H. W. Pfister, “Pathophysiology of bacterial meningitis: mechanism(s) of neuronal injury,” Journal of Infectious Diseases, vol. 186, no. 2, supplement, pp. S225–S233, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. K. Grimwood, P. Anderson, V. Anderson, L. Tan, and T. Nolan, “Twelve year outcomes following bacterial meningitis: further evidence for persisting effects,” Archives of Disease in Childhood, vol. 83, no. 2, pp. 111–116, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. X. Sáez-Llorens and G. H. McCracken, “Bacterial meningitis in children,” Lancet, vol. 361, no. 9375, pp. 2139–2148, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. M. N. Swartz, “Bacterial meningitis: a view of the past 90 years,” New England Journal of Medicine, vol. 351, no. 18, pp. 1826–1828, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. J. R. Meredith and S. Galwankar, “Clinical and epidemiological implications of meningococcal disease,” Journal of Association of Physicians of India, vol. 53, pp. 628–633, 2005. View at Google Scholar · View at Scopus
  6. Y. L. Tzeng and D. S. Stephens, “Epidemiology and pathogenesis of Neisseria meningitidis,” Microbes and Infection, vol. 2, no. 6, pp. 687–700, 2000. View at Publisher · View at Google Scholar · View at Scopus
  7. World Health Organization, “Meningogoccal meningitis,” Indian Journal of Medical Sciences, vol. 57, no. 8, pp. 369–372, 2003. View at Google Scholar
  8. M. Weisfelt, D. Van De Beek, L. Spanjaard, J. B. Reitsma, and J. De Gans, “Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series,” Lancet Neurology, vol. 5, no. 2, pp. 123–129, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. M. Arditi, E. O. Mason, J. S. Bradley et al., “Three-year multicenter surveillance of pneumococcal meningitis in children: clinical characteristics, and outcome related to penicillin susceptibility and dexamethasone use,” Pediatrics, vol. 102, no. 5, pp. 1087–1097, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. L. J. Baraff, S. I. Lee, and D. L. Schriger, “Outcomes of bacterial meningitis in children: a meta-analysis,” Pediatric Infectious Disease Journal, vol. 12, no. 5, pp. 389–394, 1993. View at Google Scholar · View at Scopus
  11. R. Nau and W. Brück, “Neuronal injury in bacterial meningitis: mechanisms and implications for therapy,” Trends in Neurosciences, vol. 25, no. 1, pp. 38–45, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. C. G. Prober, “The role of steroids in the management of children with bacterial meningitis,” Pediatrics, vol. 95, no. 1, pp. 29–31, 1995. View at Google Scholar · View at Scopus
  13. U. Koedel, W. M. Scheld, and H. W. Pfister, “Pathogenesis and pathophysiology of pneumococcal meningitis,” Lancet Infectious Diseases, vol. 2, no. 12, pp. 721–736, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. M. G. Tauber, H. Khayam-Bashi, and M. A. Sande, “Effects of ampicillin and corticosteroids on brain water content, cerebrospinal fluid pressure, and cerebrospinal fluid lactate levels in experimental pneumococcal meningitis,” Journal of Infectious Diseases, vol. 151, no. 3, pp. 528–534, 1985. View at Google Scholar · View at Scopus
  15. G. C. Townsend and W. M. Scheld, “Adjunctive therapy for bacterial meningitis: rationale for use, current status, and prospects for the future,” Clinical Infectious Diseases, vol. 17, no. 2, supplement, pp. S537–S549, 1993. View at Google Scholar · View at Scopus
  16. M. H. Lebel, B. J. Freij, G. A. Syrogiannopoulos et al., “Dexamethasone therapy for bacterial meningitis. Results of two double-blind, placebo-controlled trials,” New England Journal of Medicine, vol. 319, no. 15, pp. 964–971, 1988. View at Google Scholar · View at Scopus
  17. C. M. Odio, I. Faingezicht, M. Paris et al., “The beneficial effects of early dexamethasone administration in infants and children with bacterial meningitis,” New England Journal of Medicine, vol. 324, no. 22, pp. 1525–1531, 1991. View at Google Scholar · View at Scopus
  18. E. R. Wald, S. L. Kaplan, E. O. Mason Jr. et al., “Dexamethasone therapy for children with bacterial meningitis,” Pediatrics, vol. 95, no. 1, pp. 21–31, 1995. View at Google Scholar
  19. J. De Gans and D. Van Beek, “Dexamethasone in adults with bacterial meningitis,” New England Journal of Medicine, vol. 347, no. 20, pp. 1549–1556, 2002. View at Publisher · View at Google Scholar · View at PubMed
  20. D. van de Beek, J. de Gans, P. McIntyre, and K. Prasad, “Corticosteroids in acute bacterial meningitis,” Cochrane Database of Systematic Reviews, no. 3, Article ID CD004405, 2003. View at Google Scholar
  21. D. Van De Beek, J. De Gans, P. McIntyre, and K. Prasad, “Corticosteroids for acute bacterial meningitis,” Cochrane Database of Systematic Reviews, no. 1, Article ID CD004405, 2007. View at Publisher · View at Google Scholar · View at PubMed
  22. J. T. L. Wilson, L. E. L. Pettigrew, and G. M. Teasdale, “Structured interviews for the glasgow outcome scale and the extended glasgow outcome scale: guidelines for their use,” Journal of Neurotrauma, vol. 15, no. 8, pp. 573–580, 1998. View at Google Scholar · View at Scopus
  23. D. Van De Beek, J. De Gans, L. Spanjaard, M. Weisfelt, J. B. Reitsma, and M. Vermeulen, “Clinical features and prognostic factors in adults with bacterial meningitis,” New England Journal of Medicine, vol. 351, no. 18, pp. 1849–1923, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  24. S. I. Aronin, P. Peduzzi, and V. J. Quagliarello, “Community-acquired bacterial meningitis: risk stratification for adverse clinical outcome and effect of antibiotic timing,” Annals of Internal Medicine, vol. 129, no. 11, pp. 862–869, 1998. View at Google Scholar · View at Scopus
  25. M. L. Durand, S. B. Calderwood, D. J. Weber et al., “Acute bacterial meningitis in adults. A review of 493 episodes,” New England Journal of Medicine, vol. 328, no. 1, pp. 21–28, 1993. View at Publisher · View at Google Scholar · View at Scopus
  26. P. I. Klaaresen and T. Flaegstad, “Prognostic factors in childhood bacterial meningitis,” Acta Paediatrica, vol. 84, no. 8, pp. 873–878, 1995. View at Google Scholar · View at Scopus
  27. S. Kastenbauer and H. W. Pfister, “Pneumococcal meningitis in adults: spectrum of complications and prognostic factors in a series of 87 cases,” Brain, vol. 126, no. 5, pp. 1015–1025, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Weisfelt, D. Van De Beek, and J. De Gans, “Dexamethasone treatment in adults with pneumococcal meningitis: risk factors for death,” European Journal of Clinical Microbiology and Infectious Diseases, vol. 25, no. 2, pp. 73–78, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  29. I. Koomen, D. E. Grobbee, J. J. Roord, R. Donders, A. Jennekens-Schinkel, and A. M. Van Furth, “Hearing loss at school age in survivors of bacterial meningitis: assessment, incidence, and prediction,” Pediatrics, vol. 112, no. 5, pp. 1049–1053, 2003. View at Publisher · View at Google Scholar · View at Scopus
  30. D. A. McMillan, C. Y. Lin, S. I. Aronin, and V. J. Quagliarello, “Community-acquired bacterial meningitis in adults: categorization of causes and timing of death,” Clinical Infectious Diseases, vol. 33, no. 7, pp. 969–975, 2001. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  31. S. L. Kaplan and C. R. Woods, “Neurologic complications of bacterial meningitis in children,” Current Clinical Topics in Infectious Diseases, vol. 12, pp. 37–55, 1992. View at Google Scholar · View at Scopus
  32. S. L. Kaplan, “Clinical presentations, diagnosis, and prognostic factors of Bacterial meningitis,” Infectious Disease Clinics of North America, vol. 13, no. 3, pp. 579–594, 1999. View at Publisher · View at Google Scholar · View at Scopus