Th2 Cytokine Levels Distort the Association of IL-10 and IFN-𝛾 with Allergic Phenotypes

Table 4

Raw and adjusted IL-10 and IFN-r levels (log value) stimulated with either PHA or SEB in children with and without atopy.

	Atopy (𝑛=71)			Nonatopy (𝑛=59)			P
	Mean	95% CI		Mean	95% CI
		Lower	Upper		Lower	Upper
IL-10 (PHA)
	𝑛=71			𝑛=58
No adjustment	4.67	4.45	4.88	4.99	4.79	5.19	0.030
By IL-5	4.63	4.47	4.80	5.03	4.86	5.20	0.001
By IL-13	4.64	4.45	4.82	5.03	4.83	5.22	0.004
IL-10 (SEB)	𝑛=69			𝑛=58
No adjustment	5.47	5.31	5.62	5.70	5.51	5.89	0.062
By IL-5	5.43	5.29	5.57	5.75	5.58	5.92	0.004
By IL-13	5.45	5.32	5.59	5.72	5.54	5.89	0.017
IFN-r (PHA)
	𝑛=70			𝑛=59
No adjustment	6.11	5.84	6.38	6.50	6.29	6.71	0.026
By IL-5	6.07	5.87	6.28	6.55	6.37	6.74	0.001
By IL-13	6.08	5.85	6.31	6.54	6.34	6.75	0.003
IFN-r (SEB)	𝑛=69			𝑛=58
No adjustment	10.01	9.84	10.17	10.09	9.91	10.27	0.50
By IL-5	10.00	9.83	10.16	10.10	9.92	10.28	0.39
By IL-13	10.00	9.83	10.17	10.10	9.92	10.27	0.44