Complement C3 Genotype Variants and Risk of Lung Cancer Mortality

Table 1

Lifestyle and other characteristics of men with the complement C3 FS/FF compared to men with the complement C3 SS genotype.

	C3 genotype
	FS/FF	SS	𝑃
Subjects 𝑛	1122	2075
Age years	62.7 ± 5.1	63.1 ± 5.2	0.05
Dietary factors
Salt^#	11.6	12.7	0.36
Fat^¶	51.7	51.4	0.90
Smoking
Cumulative pack-years	28.5 ± 27.2	27.9 ± 24.5	0.54
Current	56.0	54.1	0.31
Cotinine level,	47.6	49.5
<100 ng/mL
100–360 ng/mL	25.1	25.1	0.48
>360 ng/mL	27.3	25.4
Smoking 1970/71	68.0	68.4	0.80
Never	11.9	10.7	0.28
Alcohol use
Consumption
0 drinks/week	12.0	10.6
1–21 drinks/week	57.8	62.8	0.02
≥22 drinks/week	30.2	26.5
Beer	73.7	74.3	0.75
Wine	54.9	53.4	0.42
Spirits intake	53.7	51.3	0.20
Long-term occupational dust exposure	7.9	7.5	0.67

Data are presented as mean ± SD or percentages; ^#uses more than others; ^¶does not avoid fatty foods;
𝑃-values of unpaired 𝑡-test or Chi-squared test (likelihood ratio) as appropriate.