Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011, Article ID 426150, 3 pages
Case Report

Breast Metastatic Localization of Signet-Ring Cell Gastric Carcinoma

Servicio de Obstetricia y Ginecología, Hospital Marina Baixa, Avenida Alcalde En Jaume Botella Major 7, 03570 Villajoyosa (Alicante), Spain

Received 26 August 2010; Accepted 21 October 2010

Academic Editor: C. Mundhenke

Copyright © 2011 C. Parrell Soler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Metastatic tumors in the breast are quite rare and constitute 0,5 to 6% of all breast malignancies. They often occur in a polymetastatic context. Gastrointestinal lesions rarely metastasize to the breast. The first case of a metastasis deposit to the breast and ovary from gastric signet-ring cell carcinoma was reported in the literature in 1999. Since this report, only 5 cases have been reported. We present a case report of a 37-year-old woman who complained of a lump in the left breast. Two months earlier, the woman underwent a subtotal gastrectomy and a total hysterectomy with double anexectomy, which histologically was diagnosed of gastric signet-ring carcinoma, disseminated with Krukenberg's tumor. In those days, the patient was following a chemotherapy treatment. A core needle biopsy of the lesion in left breast revealed cells with signet-ring features, with probably gastric origin.