Research Article

A Remarkably High-Speed Solution-Phase Combinatorial Synthesis of 2-Substituted-Amino-4-Aryl Thiazoles in Polar Solvents in the Absence of a Catalyst under Ambient Conditions and Study of Their Antimicrobial Activities

Table 1

Screening of IL in combination with various dipolar aprotic solvents.

Sr. no.IL+ dipolar aprotic solventsReaction time (sec)

1(bbim)+Br + DMSO30–40
2(bbim)+Br + DMF30–40
3(bbim)+Br + acetonitrile30–40
4(bbim)+Br + Dioxane60