International Scholarly Research Notices / 2011 / Article / Tab 3

Research Article

A Remarkably High-Speed Solution-Phase Combinatorial Synthesis of 2-Substituted-Amino-4-Aryl Thiazoles in Polar Solvents in the Absence of a Catalyst under Ambient Conditions and Study of Their Antimicrobial Activities

Table 3

Synthesis of 2-substitued-amino-4-aryl thiazoles.

ArRThiazolesTime (Sec.)Yielda (%)

C6H5H3a30–4096
C6H5C6H53b30–4093
C6H5CH33c30–4092
C6H5CH2CH2C6H43d (Fanetizole)30–4091
C6H54-Cl C6H43e30–4092
C6H54-NO2 C6H43f30–4092
C6H54-F C6H43g30–4093
4-Cl C6H4H3h30–4094
4-Cl C6H4C6H53i30–4093
4-Cl C6H4CH33j30–4091
4-Cl C6H44-Cl C6H43k30–4092
4-Cl C6H44-NO2 C6H43l30–4092
4-Cl C6H44-F C6H43m30–4094
4-Br C6H4H3n30–4095
4-Br C6H4C6H53o30–4092
4-Br C6H4CH33p30–4091
4-Br C6H44-Cl C6H43q30–4094
4-Br C6H44- CH3C6H43r30–4092
4-Br C6H44-F C6H43s30–4093
4-CH3C6H4H3t18093
4-CH3C6H4C6H53u18094
4-CH3C6H4CH33v18094
4-CH3C6H44-CH3 C6H43w18091
4-CH3C6H44-Cl C6H43x18093
4-CH3C6H44-F C6H43y18092

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