Table of Contents
ISRN Surgery
Volume 2011, Article ID 451020, 4 pages
Research Article

Pilot Study on the Efficiency of the Biostimulation with Autologous Plasma Rich in Platelet Growth Factors in Otorhinolaryngology: Otologic Surgery (Tympanoplasty Type I)

1Department of Otorhinolaryngology, Vall d'Hebron Hospital, Autonomous University of Barcelona, 08035 Barcelona, Spain
2Blood-Tissues Bank, Vall d'Hebron Hospital, Autonomous University of Barcelona, 08035 Barcelona, Spain

Received 7 March 2011; Accepted 28 April 2011

Academic Editor: E. C. Tsimoyiannis

Copyright © 2011 María Luisa Navarrete Álvaro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


When otologic procedures that involve tympanic membrane repairs are performed, biomaterials or biological tissues as normal as grafts are used. At the moment, biological material from the own patient is used with varying success rates. The procedure used and the patient's tissue repair capabilities tend to determine the outcome. We present a preliminary study on tympanic membrane perforation repairs using an autograft obtained by manipulating platelet degranulation and the coagulation cascade and reinforced with a seal using platelet growth factors. We present three cases in which we used this procedure. The results will be valued based on the tympanic perforation closure index. With this study, we want to assess the effectiveness of tympanic perforation repairs with this technically simple method. If this method was objectively proved to be effective, it would lead to lower patient morbidity and sanitary costs.