Research Article

Development of Topical Niosomal Gel of Benzoyl Peroxide

Table 5

Table shows data of optimization of solvent system.

Formulation codeChloroformMethanolVolume of solvent systemPercentage drug entrapments ± %SDAverage particle size ± %SD

NF29111082.26% (±1.89)4.67 (±0.09)
NF30211056.55% (±1.98)5.23 (±0.21)
NF21121092.16% (±2.43)4.78 (±0.09)
NF3112572.02% (±3.25)6.68 (±0.08)
NF32122080.35% (±2.77)7.51 (±0.33)

𝑛 = 3 ; Batch F21 was taken and studied for the best solvent system to get maximum PDE.