Development of Topical Niosomal Gel of Benzoyl Peroxide

Table 8

Table shows final optimized batch.

Serial No.	Parameters	Optimized value
1	Nonionic surfactant	Span 80
2	Drug : cholesterol : surfactant molar ratio	1 : 1.5 : 3
3	Solvent system	Chloroform : methanol, 1 : 2
4	Hydration temperature	60°C
5	Vacuum	20 mmHg
6	Speed of rotation	50 rpm
7	Hydration volume	7 mL
8	Hydration time	2 hour
9	Annealing time	1 hour