Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats

Table 4

Effect of Hypericum perforatum on plasma lipid parameters in high-fat-induced obese rats.

Group (𝑛=6)	Total-C (mg/dL)	HDL-C (mg/dL)	LDL-C (mg/dL)	Triglyceride (mg/dL)
Normal control (NPD + CMC)	53.60 ± 2.27	34.65 ± 0.92	33.55 ± 3.07	53.60 ± 2.27
HFD control (HFD + CMC)	105.03 ± 4.87**	24.62 ± 0.79**	116.49 ± 6.68**	105.03 ± 4.87**
HFD + HpE 100 mg/kg	86.27 ± 2.51^**††	28.24 ± 0.89^**†	80.72 ± 3.83^**†††	86.27 ± 2.51^**††
HFD + HpE 200 mg/kg	80.42 ± 3.61^**†††	30.19 ± 0.93^*†††	62.85 ± 4.21^**†††	80.40 ± 3.61^**†††

^∗𝑃<.01,^∗∗𝑃<.001 versus normal control; ^†𝑃<.05,^††𝑃<.01,^†††𝑃<.001 versus HFD control.