Separation and Quantification of Eight Antidiabetic Drugs on A High-Performance Liquid Chromatography: Its Application to Human Plasma Assay

Table 4

Recovery of eight anti-diabetic drugs from plasma samples spiked with each drug spiked.

Compound	Concentrations (ng/mL)				% recovery and  % RSD
	LLOQ	LQC	MQC	HQC	LLOQ	LQC	MQC	HQC
ROS	24.3	53.7	489.2	1531.0	80.1, 9.1	77.2, 11.3	81.5, 7.2	83.4, 6.9
PIO	36.1	48.9	491.2	1513.8	82.4, 7.3	80.6, 10.1	81.9, 8.1	82.3, 7.2
GLP	35.6	50.6	492.3	1498.5	80.9, 6.7	81.9, 14.7	82.3, 7.7	84.0, 9.8
GLC	30.5	46.8	486.7	1467.0	79.9, 5.9	84.5, 12.6	83.2, 11.1	79.7, 13.9
REP	20.2	49.2	493.4	1502.7	84.5, 4.9	80.8, 14.2	80.9, 8.7	82.4, 9.7
NGL	20.6	52.9	478.6	1439.6	80.8, 8.8	83.4, 13.7	82.1, 12.4	80.9, 10.6
GLB	40.1	45.7	478.5	1452.0	79.1, 10.3	75.5, 12.2	78.9, 12.7	76.8, 12.3
GLM	38.4	48.6	490.5	1477.5	81.2, 10.7	78.2, 11.0	80.1, 4.7	80.1, 10.