Review Article

Obesity, Visceral Fat, and NAFLD: Querying the Role of Adipokines in the Progression of Nonalcoholic Fatty Liver Disease

Table 6

Differences in adipocytokines expression between visceral and subcutaneous fat in humans [28, 38, 4952, 57, 6367, 75].

AdipocytokineDifferences in expression

AdiponectinVF < SCF
AdipsinVF < SCF
ASPVF < SCF
CETPVF < SCF
Leptin/Ob-ReVF < SCF
TNF-αVF = SCF
AngiotensinogenVF > SCF
Factor BVF > SCF
Il-6VF > SCF
IL-8VF > SCF
PAI-1VF > SCF
PPAR-γVF > SCF
ResistinVF > SCF
VEGFVF > SCF
11β-HSD type 1VF > SCF
MCP-1VF > SCF
VisfatinVF > SCF
OmentinVF > SCF

11βHSD type 1: 11-hydroxy-steroid-dehydrogenase type 1; ASP: acylation stimulation protein; CETP: cholesterol ester transfer protein; IL-6: interleukin-6; IL-8: interleukin-8; PAI-1: plasminogen activator inhibitor-1; PPAR-γ: peroxisome proliferators-activated receptor-γ; SCF: subcutaneous fat; TNF-α: tumour necrosis factor-α; VF: visceral fat; VEGF, vascular endothelial growth factor; MCP-1: monocyte chemoattractant protein-1.