Efficacy and Safety of Deracoxib for the Control of Postoperative Pain and Inflammation Associated with Dental Surgery in Dogs

Table 3

Frequency and distribution of adverse clinical observations reported for all dogs enrolled in the study, including adverse clinical observations reported after intervention therapy and observations reported by the owners after the dog returned home.

Clinical observation	Number of dogs with reported adverse clinical observations*
	Deracoxib 𝑛=31	Placebo 𝑛=31
Vomiting	4	1
Regurgitation	0	2
Diarrhea/soft stool	3	1
Increased AST^†	3	0
Increased ALT^†	1	0
Hematuria	1	0
Leukocytosis	1	1
Neutrophilia	1	1
Lameness	1	0
Facial swelling	0	1
Tachycardia	0	1

*Dogs may have experienced more than one of the observations during the study.
^†Includes animals with results over 2x the high normal.