Thio Analogs of Pyrimidine Bases: Synthesis, Spectroscopic Study, and In Silico Biological Activity Evaluation of New 2-o-(m- and p-)Chlorobenzylthio-6-Methyl-5-Piperidino-(Morpholino-)Methyluracils

Table 4

Physical and analytical data of compounds 1–6.

Comp.	Formula MW	Yield [%]	M.p. [°C]	Rf TLC*	Analysis
					Calculated			Found
					C	H	N	C	H	N
1	C18H22N3SOCl 363.90	58	183-3	0.21	59.12	5.89	11.55	59.00	5.60	11.40
2	C18H22N3SOCl 363.90	35	147-8	0.20	59.12	5.89	11.55	59.59	5.72	11.60
3	C18H22N3SOCl 363.90	67	99-100	0.23	59.12	5.89	11.55	59.10	5.80	11.28
4	C17H20N3SO2Cl 365.88	62	175-6	0.30	55.81	5.51	11.48	55.53	5.24	11.21
5	C17H20N3SO2Cl 365.88	23	134-5	0.31	55.81	5.51	11.48	55.82	5.34	11.16
6	C17H20N3SO2Cl 365.88	56	177-8	0.32	55.81	5.51	11.48	55.58	5.30	11.24

*CHCl₃ : CH₃OH, 10 : 1.