Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology

<table>(a) Response surface plot showing the influence of drug-to-polymer ratio and stirring speed on mean particle size (<i>μ</i>m) and (b) corresponding contour plot showing the relationship between various levels of 2 independent variables.</table>

International Scholarly Research Notices

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Figure 2

Figure 2: Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology 