Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology

Table 2

Summary of results of regression analysis.

Coefficient	𝑏0	𝑏1	𝑏2	𝑏11	𝑏22	𝑏12	R^2
Entrapment efficiency (%)	59.07	8.33	−3.50	0.50	−1.24	1.26	0.9970
Mean particle size (μm)	244.38	32.83	−8.83	−1.50	1.67	−0.33	0.9979
𝑡80% release (min)	348.79	124.33	−19.67	−24.00	79.72	−42.28	0.9694