Diffusion Tensor Imaging for In Vivo Detection of Degenerated Optic Radiation
Table 1
Characteristics of the case reports.
Case
Control
ID
HS
JS
Age [yr]
68
25
Gender
F
F
Concomitant diseases
HT, HC stroke 12 yr ago
Crohn’s disease
DTI diagnosis of optic radiation
Rarefication L > R
Vigorously and completely developed
MRI diagnosis
Moderate cerebral microangiopathy, level 2
No cerebral microangiopathy
OD
OS
OD
OS
Eye diagnosis
POAG
POAG, parapapillary bleeding
Vital papilla
Vital papilla
Visual acuity
1.0
0.6
1.25
1.0
IOP [mm Hg](Case with local therapy)
18
17
14
11
Octopus MD [dB]
3.6
6.6
−0.6
0.3
FDT (≤50 sec)
42
74
36
34
HRT Disc area (1.69–2.82 mm2)
1.855
1.718
HRT Cup area (0.26–1.27 mm2)
0.269
0.166
HRT Rim area (1.20–1.78 mm2)
1.586
1.552
Right OR
Left OR
Right OR
Left OR
DTI Voxel No.
575
470
848
717
F: female; OD: right eye; OS: left eye; OR: optic radiation; POAG: primary open-angle glaucoma; IOP: intraocular pressure, MD: mean defect; FDT: frequency doubling test (loss of spatial-temporal contrast sensitivity: A mild relative >95%, B moderate relative >98%, C severe >99%; number of fields of a maximum of 17); HRT: Heidelberg Retina Tomograph; DTI: diffusion tractography imaging; HT: arterial hypertension; HC: hypercholesterolemia.