Formulation and Evaluation of Transdermal Patch of Repaglinide

Table 1

Preliminary trial batches.

Batch code	Polymer	Polymer proportion	Solvent	Plasticizer (30% w/w)*
P1	PVA : PVP	1 : 1	Water	PG
P2	HPMC K100M : PVP	1 : 1	Water	PEG
P3	HPMC K4M : PVP	1 : 1	Water	PEG
P4	EC : PVP	1 : 4	CHCl3	PG
P5	EC : HPMC K4M	3 : 7	Ethanol : DCM	PEG

Each batch contains 4 mg drug in 4 cm² area. *30% w/w of total polymer weight.