Formulation and Evaluation of Transdermal Patch of Repaglinide

Table 6

Calculation for testing the model in portions.

Tensile strength
	DF	SS	MS	𝐹	𝑅^2
Regression
FM	5	0.345469	0.069094	9.924378	0.94299	𝐹cal=0.4047080856747338
RM	2	0.337017	0.168508	34.46109	0.91992	𝐹tab=9.27663
Error
FM	3	0.020886	0.006962	–	–	DF (3,3)
RM	6	0.029339	0.00489	–	–
For 𝑄1
	DF	SS	MS	𝐹	𝑅^2
Regression
FM	5	89.24479	17.84896	8.196259	0.93179	𝐹cal=3.209464
RM	1	61.28835	61.28835	12.43909	0.6399	𝐹tab=9.11718
Error
FM	3	6.533088	2.177696	–	–	DF (4,3)
RM	7	34.48953	4.927076	–	–
For 𝑄9
	DF	SS	MS	𝐹	𝑅^2
Regression
FM	5	3386.258	677.2515	16.42181	0.964751	𝐹cal=2.50177555838715
RM	1	2973.555	2973.555	38.80292	0.847171	𝐹tab=9.11718
Error
FM	3	123.723	41.24098	–	–	DF (4,3)
RM	7	536.4257	76.63224	–	–
For Diffusion coefficient
	DF	SS	MS	𝐹	𝑅^2
Regression
FM	5	0.172597	0.034519	2.445924	0.80302	𝐹cal=3
RM	–	–	–	–	–	𝐹tab=9.013455168
Error
FM	3	0.042339	0.014113	–	–	DF (5,3)
RM	–	–	–	–	–

*DF: degree of freedom; SS: sum of squares; MS: mean of squares; 𝑅²: regression coefficient; FM: full model; RM: reduced model.