Table of Contents
ISRN Cardiology
Volume 2011, Article ID 659787, 5 pages
Research Article

What Happens before Syncope? Study of the Time Frame Preceding Vasovagal Syncope

Dipartimento di Medicina Interna, Ospedale Santa Maria Nuova, Piazza S. Maria Nuova, 50100 Firenze, Italy

Received 21 February 2011; Accepted 18 March 2011

Academic Editors: T. Kuusela and E. Liehn

Copyright © 2011 Alfonso Lagi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The events characterizing the very last part of the vasovagal crisis has not been determined. The aim of the study was to analyze the variations in respiratory pattern preceding the vaso-vagal syncope full-blown and the relationship between cardiovascular functions in order to assess the temporal sequence. Methods. Eleven consecutive patients were studied. Heart rate, arterial pressure, respiratory frequency, tidal volume, carbon dioxide, and oxygen saturation in time domain from supine and standing recordings were analyzed. Results. The respiratory activity is different in the time frame preceding syncope, both in VT and breathing rate, and that the increase of the lung ventilation does not influence the baroreflex control during the presyncopal period but may be cause of the baroreflex failure during the full-blown syncope.