Clinical Study

Incidence of Vasospasm, Outcome, and Quality of Life after Endovascular and Surgical Treatment of Ruptured Intracranial Aneurysms: Results of a Single-Center Prospective Study in Switzerland

Table 4

Outcome and quality of life after surgical and endovascular occlusion of the aneurysm.

Surgical Treatment 𝑃 value surgical 𝑃 value CVS surgicalEndovascular treatment
Totalclinical CVSno clinical CVSversus endovascularversus CVS endovascularTotalclinical CVSno clinical CVS

Survivors/total patients35/417/1228/2924/255/619/19
Survivors (%)85.458.396.69683.3100
Mortality (%)14.641.63.4NSNS416.70
mRS 1 . 5 ± 2 . 2 2 . 8 ± 3 0 . 9 ± 1 . 5 NSNS 1 . 5 ± 1 . 9 3 . 3 ± 2 . 1 0 . 8 ± 1 . 3
MMSE* 2 8 . 4 ± 3 . 3 2 9 . 1 ± 0 . 9 2 8 . 2 ± 3 . 6 NSNS 2 8 . 9 ± 2 2 7 . 3 ± 3 . 7 2 9 . 3 ± 1 . 4
NIHSS* 1 . 3 ± 5 . 3 4 . 9 ± 1 1 . 1 0 . 3 ± 0 . 8 NSNS 4 . 7 ± 1 4 . 6 7 . 4 ± 1 1 . 0 3 . 9 ± 1 5 . 3
Barthel-Index* 9 7 . 5 ± 7 . 6 9 7 . 9 ± 5 . 2 9 7 . 4 ± 8 . 1 NSNS 8 8 . 4 ± 2 9 . 6 6 9 ± 4 0 . 3 9 4 . 1 ± 2 3 . 5
EQ-5D (%) *:51.514.361.5NS 𝑃 < 𝟎 . 𝟎 𝟓 52.28044.4
 Mobility (%)12.114.39.1 𝑃 < 𝟎 . 𝟎 𝟓 𝑃 < 𝟎 . 𝟎 𝟓 34.88022.2
 Self-Care (%)12.1015.4NS 𝑃 < 𝟎 . 𝟎 𝟓 21.76011.1
 Usual activities (%)27.314.330.8NS 𝑃 < 𝟎 . 𝟎 𝟓 39.18027.8
 Pain/Discomfort (%)30.3038.5NS 𝑃 < 𝟎 . 𝟎 𝟓 39.16033.3
 Anxiety/Depression (%)24.214.326.9NSNS21.76011.1
 Patients’ health (VAS) 7 7 . 3 ± 1 7 . 2 8 5 ± 1 4 7 5 ± 1 7 NSNS 7 7 . 1 ± 1 6 . 5 6 3 ± 1 5 8 0 ± 1 5
SF-12 :
 PCS48.6949.7548.36NSNS48.2241.3449.44
 MCS43.1844.2342.85NSNS45.4735.4647.42

CVS: cerebral vasospasm; mRS: modified Rankin Score; MMSE: Minimental State Examination; NIHSS: National Institutes of Health Stroke Scale; NS: no statistically significant. *: measurements in survivors. EQ-5D: EuroQoL health state; VAS: visual analog scale for patients’ health state (0–100); *: patients reporting problems in at least one of the EuroQol items. : patients presenting with any limitation (level 2 or 3); SF-12: Short Form-12; PCS: physical component summary; MCS: mental component summary; : measurements based on 30 out of 35 patients in the surgical group and 20 out of 24 in the endovascular group. All data are expressed as mean ± standard deviation.