International Scholarly Research Notices / 2011 / Article / Fig 3

Research Article

Autoantibodies to the 𝜷 𝟏 -Adrenoceptor from Patients with Periodontitis as a Risk Factor for Cardiac Dysfunction

Figure 3

Effect of increasing concentrations of anti-Ξ² 1-AR peptide IgG (IgG) on contractility (dF/dt) and production of cAMP and cGMP in isolated atria from rats. (a) Comparative effects of anti-Ξ² 1-AR peptide IgG on dF/dt (β€’-β€’) and on cAMP production (β—‹-β—‹). (b) Comparative effects of anti-Ξ² 1-AR peptide IgG on dF/dt (β€’-β€’) and on cGMP production (β—‹-β—‹). (c) Positive correlation between cAMP and dF/dt (corresponding data to A values). (d) Negative correlation between cGMP and dF/dt (corresponding data to B values). Values are mean Β± s.e.m. of 20 patients with periodontitis.
791393.fig.003

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