Dementia Enhances Inhibitory Actions of General Anesthetics in Hippocampal Synaptic Transmission

<table>Effects of sevoflurane (3.0 vol%) inhalation on time for loss of righting reflex (LORR) in dementia model mice (SAM-P8, <svg height="11.1" id="M2" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 11.1" width="35.099998" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="21.71771" y="0">5</tspan>
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</svg>) and control mice (SAM-R1, <svg height="11.1" id="M3" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 11.1" width="35.099998" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">5</tspan>
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</svg>). Data were expressed as mean ± SD. <svg height="15.65" id="M4" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 72.912498 15.65" width="72.912498" xmlns="http://www.w3.org/2000/svg">
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<g transform="translate(72,-59.48)">
<text transform="matrix(1,0,0,-1,-69.87,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
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<text transform="matrix(1,0,0,-1,-64.79,62.66)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="44.810753" y="0">3</tspan>
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</svg>.</table>

International Scholarly Research Notices

fig1

Figure 1

Figure 1: Dementia Enhances Inhibitory Actions of General Anesthetics in Hippocampal Synaptic Transmission 