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International Scholarly Research Notices

International Scholarly Research Notices / 2011 / Article / Tab 2

Clinical Study

A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

Table 2

Changes of UPDRS, UPDRSm, Modified Hoehn and Yahr stage, and Schwab and England ADL scale by rTMS (sham and real).
(a)
Before rTMSAfter sham rTMSAfter real rTMS š‘ƒ value
Drug-onUPDRS 4 8 . 4 5 Ā± 1 2 . 3 6 4 3 . 5 8 Ā± 1 2 . 3 3 4 0 . 1 5 Ā± 1 1 . 9 9 0.006*
m H & Y 2 . 9 2 Ā± 0 . 5 6 2 . 7 5 Ā± 0 . 6 9 2 . 8 8 Ā± 0 . 5 7 0.132
S&E 7 3 . 3 3 Ā± 1 4 . 3 5 7 2 . 5 0 Ā± 1 5 . 4 5 7 5 . 0 0 Ā± 1 4 . 4 6 0.442
Drug-offUPDRS 5 3 . 5 5 Ā± 1 9 . 9 6 4 8 . 7 8 Ā± 1 4 . 3 2 4 4 . 2 9 Ā± 1 5 . 4 0 0.003*
m H & Y 2 . 9 2 Ā± 0 . 5 6 2 . 9 2 Ā± 0 . 7 0 2 . 8 8 Ā± 0 . 5 7 0.590
S&E 7 0 . 0 0 Ā± 1 7 . 0 6 6 7 . 5 0 Ā± 1 8 . 6 5 7 3 . 3 3 Ā± 1 3 . 7 1 0.093
Repeated measures ANOVA. * š‘ƒ < 0 . 0 5 .
(b)
Before rTMSAfter sham rTMSAfter real rTMSSham (1)Real (2)Overall (3)
Drug-onUPDRS 4 8 . 4 5 Ā± 1 2 . 3 6 4 3 . 5 8 Ā± 1 2 . 3 3 4 0 . 1 5 Ā± 1 1 . 9 9 0.0660.029*0.005*
Drug-offUPDRS 5 3 . 5 5 Ā± 1 9 . 9 6 4 8 . 7 8 Ā± 1 4 . 3 2 4 4 . 2 9 Ā± 1 5 . 4 0 0.4540.015*0.026*
Paired š‘” -test with Bonferroni correction. * š‘ƒ < 0 . 0 5 . Drug-on: taking drugs as prescribed, drug-off: according to Table 2. UPDRS: unified Parkinson's Disease Rating Scale. S&E: Schwab and England ADL scale, mH & Y: modified Hoehn and Yahr stage. (1): š‘ƒ value for between before rTMS and after sham rTMS. (2): š‘ƒ value for between after sham rTMS and after real rTMS. (3): š‘ƒ value for between before rTMS and after real rTMS.