International Scholarly Research Notices / 2011 / Article / Tab 2

Clinical Study

A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

Table 2

Changes of UPDRS, UPDRSm, Modified Hoehn and Yahr stage, and Schwab and England ADL scale by rTMS (sham and real).
(a)

Before rTMSAfter sham rTMSAfter real rTMS 𝑃 value

Drug-onUPDRS 4 8 . 4 5 ± 1 2 . 3 6 4 3 . 5 8 ± 1 2 . 3 3 4 0 . 1 5 ± 1 1 . 9 9 0.006*
m H & Y 2 . 9 2 ± 0 . 5 6 2 . 7 5 ± 0 . 6 9 2 . 8 8 ± 0 . 5 7 0.132
S&E 7 3 . 3 3 ± 1 4 . 3 5 7 2 . 5 0 ± 1 5 . 4 5 7 5 . 0 0 ± 1 4 . 4 6 0.442

Drug-offUPDRS 5 3 . 5 5 ± 1 9 . 9 6 4 8 . 7 8 ± 1 4 . 3 2 4 4 . 2 9 ± 1 5 . 4 0 0.003*
m H & Y 2 . 9 2 ± 0 . 5 6 2 . 9 2 ± 0 . 7 0 2 . 8 8 ± 0 . 5 7 0.590
S&E 7 0 . 0 0 ± 1 7 . 0 6 6 7 . 5 0 ± 1 8 . 6 5 7 3 . 3 3 ± 1 3 . 7 1 0.093

Repeated measures ANOVA. * 𝑃 < 0 . 0 5 .
(b)

Before rTMSAfter sham rTMSAfter real rTMSSham (1)Real (2)Overall (3)

Drug-onUPDRS 4 8 . 4 5 ± 1 2 . 3 6 4 3 . 5 8 ± 1 2 . 3 3 4 0 . 1 5 ± 1 1 . 9 9 0.0660.029*0.005*
Drug-offUPDRS 5 3 . 5 5 ± 1 9 . 9 6 4 8 . 7 8 ± 1 4 . 3 2 4 4 . 2 9 ± 1 5 . 4 0 0.4540.015*0.026*

Paired 𝑡 -test with Bonferroni correction. * 𝑃 < 0 . 0 5 . Drug-on: taking drugs as prescribed, drug-off: according to Table 2. UPDRS: unified Parkinson's Disease Rating Scale. S&E: Schwab and England ADL scale, mH & Y: modified Hoehn and Yahr stage. (1): 𝑃 value for between before rTMS and after sham rTMS. (2): 𝑃 value for between after sham rTMS and after real rTMS. (3): 𝑃 value for between before rTMS and after real rTMS.