Table of Contents
ISRN Pulmonology
Volume 2011, Article ID 876534, 7 pages
Review Article

Smoking and Other Interstitial Lung Diseases

Department of Pneumology, La Paz University Hospital, Paseo de la Castellana 261, 28046 Madrid, Spain

Received 12 May 2011; Accepted 3 June 2011

Academic Editors: K. Nishimura and M. Tatar

Copyright © 2011 Carpio Carlos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cigarette smoking has been implicated in the development of some uncommon respiratory interstitial diseases. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung diseases are characterized by a diffuse alveolar and peribronchiolar filling with macrophages, respectively. Pulmonary Langerhans' cell histiocytosis is a rare interstitial lung disorder characterized by the proliferation of Langerhans' cell forming interstitial infiltrates and nodules that could progress to cavitary nodules. The treatment of these disorders involves smoking cessation and sometimes the use of steroids. High-resolution computed tomography is essential for the characterization of these smoking-related interstitial lung diseases, but frequently it is necessary to create a workgroup composed by pulmonologists, pathologists, and radiologists to diagnosis and treat patients affected with these pathologies.