Table of Contents
ISRN Cardiology
Volume 2011 (2011), Article ID 897908, 5 pages
http://dx.doi.org/10.5402/2011/897908
Research Article

Relationship between Younger Age, Autoimmunity, Cardiometabolic Risk, Oxidative Stress, HAART, and Ischemic Stroke in Africans with HIV/AIDS

1Faculty of Health Sciences, Walter Sisulu University, Mthatha 5117, South Africa
2Department of Internal Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo
3Department of Radiology, Kinshasa University, Democratic Republic of Congo
4University of Marien Ngouabi, Brazzaville, Democratic Republic of Congo
5Lomo Medical Cardiovascular Centre for Africa, Limete, Kinshasa, Democratic Republic of Congo

Received 28 January 2011; Accepted 22 March 2011

Academic Editor: J. Wang

Copyright © 2011 Benjamin Longo-Mbenza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. J. Palella Jr., K. M. Delaney, A. C. Moorman et al., “Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection,” The New England Journal of Medicine, vol. 338, no. 13, pp. 852–860, 1998. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. A. Mocroft, R. Brettle, O. Kirk et al., “Changes in the cause of death among HIV positive subjects across Europe: results from the EuroSIDA study,” AIDS, vol. 16, no. 12, pp. 1663–1671, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Mochan, M. Modi, and G. Modi, “Stroke in black South African HIV-positive patients: a prospective analysis,” Stroke, vol. 34, no. 1, pp. 10–15, 2003. View at Publisher · View at Google Scholar
  4. T. H. Brannagan III, “Retroviral-associated vasculitis of the nervous system,” Neurologic Clinics, vol. 15, no. 4, pp. 927–944, 1997. View at Publisher · View at Google Scholar
  5. B. Longo-Mbenza, E. Lukoki Luila, P. Mbete, and E. Kintoki Vita, “Is hyperuricemia a risk factor of stroke and coronary heart disease among Africans?” International Journal of Cardiology, vol. 71, no. 1, pp. 17–22, 1999. View at Publisher · View at Google Scholar
  6. B. Longo-Mbenza, J. Nkondi Nsenga, and D. Vangu Ngoma, “Prevention of the metabolic syndrome insulin resistance and the atherosclerotic diseases in Africans infected by Helicobacter pylori infection and treated by antibiotics,” International Journal of Cardiology, vol. 121, no. 3, pp. 229–238, 2007. View at Publisher · View at Google Scholar · View at PubMed
  7. B. Longo-Mbenza, R. M. Ngimbi, D. V. Ngoma, S. M. Fuele, and B. Buassa-bu-Tsumbu, “Risk factors of stroke among Congolese black hypertensive diabetics,” Annales de Cardiologie et d'Angeiologie, vol. 57, no. 1, pp. 37–43, 2008. View at Publisher · View at Google Scholar · View at PubMed
  8. B. Longo-Mbenza, J. C. Manzala Kumbi, G. Milongo Dipa, A. Nge Okwe, and S. Mbungu Fuele, “Association between coronary heart disease, certain components of metabolic syndrome and the QTc interval in hypertensive central Africans,” Circulation, vol. 117, 2008, [abstract no. P680]. View at Google Scholar
  9. Anonymous, “Guidelines subcommittee World Health Organization—International Society of Hypertension Guidelines for the Management of Hypertension,” Journal of Hypertension, vol. 17, pp. 151–183, 1999. View at Google Scholar
  10. American Diabetes Association, “Report of the expert committee on the diagnosis and classification of diabetes mellitus,” Diabetes Care, vol. 20, no. 7, pp. 1183–1197, 1997. View at Google Scholar
  11. S. Hatano, “Experience from a multicentre stroke register: a preliminary report,” Bulletin of the World Health Organization, vol. 54, no. 5, pp. 541–553, 1976. View at Google Scholar
  12. S. C. Kunitz, C. R. Gross, A. Heyman et al., “The pilot stroke data bank: definition, design, and data,” Stroke, vol. 15, no. 4, pp. 740–746, 1984. View at Google Scholar
  13. K. G. M. M. Alberti, P. Zimmet, and J. Shaw, “The metabolic syndrome—a new worldwide definition,” The Lancet, vol. 366, no. 9491, pp. 1059–1062, 2005. View at Publisher · View at Google Scholar · View at PubMed
  14. B. Longo-Mbenza, E. Bieleli, E. Muls, N. Vangu, and S. Ditu Mpadamadi, “The role of early hemodynamic impairment and disease duration on diabetic cardiomyopathy and hypertension in central Africans with atherosclerosis,” Journal of Diabetes and its Complications, vol. 16, no. 2, pp. 146–152, 2002. View at Publisher · View at Google Scholar
  15. B. Longo-Mbenza, J. B. Kasiam Lasi On'Kin, A. Nge Okwe, D. Vangu, S. Mbungu, and G. Milongo, “Comparison of abdominal obesity and total obesity in predicting risk of prehypertension status with reference to economic development in the South-West of Congo Kinshasa,” Circulation, vol. 118, Article ID e448, 2008, [abstract no. 0169]. View at Google Scholar
  16. B. Longo-Mbenza, J. B. Kasiam, J. C. Manzala Kumbi et al., “Relation of QT interval with different definitions and components of metabolic syndrome in central African patients,” Circulation, vol. 117, 2008, [abstract no. P949]. View at Google Scholar
  17. World Health Organization, “Acquired immune deficiency syndrome (AIDS): interim proposal for a WHO staging system for HIV-A infection and disease,” The Weekly Epidemiological Record, vol. 65, pp. 221–228, 1990. View at Google Scholar
  18. Centers for disease control and prevention, “1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults,” Morbidity and Mortality Weekly Report, vol. 41, no. RR-17, pp. 1–19, 1992. View at Google Scholar
  19. A. A. Rabinstein, “Stroke in HIV-infected patients: a clinical perspective,” Cerebrovascular Diseases, vol. 15, no. 1-2, pp. 37–44, 2003. View at Publisher · View at Google Scholar
  20. J. R. Berger, J. O. Harris, J. Gregorios, and M. Norenberg, “Cerebrovascular disease in AIDS: a case-control study,” AIDS, vol. 4, no. 3, pp. 239–244, 1990. View at Google Scholar · View at Scopus
  21. M. D. Connor, G. A. Lammie, J. E. Bell, C. P. Warlow, P. Simmonds, and R. D. Brettle, “Cerebral infarction in adult AIDS patients: observations from the Edinburgh HIV Autopsy Cohort,” Stroke, vol. 31, no. 9, pp. 2117–2126, 2000. View at Google Scholar · View at Scopus
  22. A. I. Qureshi, R. S. Janssen, J. M. Karon et al., “Human immunodeficiency virus infection and stroke in young patients,” Archives of Neurology, vol. 54, no. 9, pp. 1150–1153, 1997. View at Google Scholar · View at Scopus
  23. A. R. Gillams, E. Allen, K. Hrieb, N. Venna, D. Craven, and A. P. Carter, “Cerebral infarction in patients with AIDS,” American Journal of Neuroradiology, vol. 18, no. 8, pp. 1581–1585, 1997. View at Google Scholar · View at Scopus
  24. B. O. Osuntokun, O. Bademosi, O. O. Akinkugbe, A. B. O. Oyediran, and R. Carlisle, “Incidence of stroke in an African city: results from the stroke registry at Ibadan, Nigeria, 1973–1975,” Stroke, vol. 10, no. 2, pp. 205–207, 1979. View at Google Scholar · View at Scopus
  25. E. S. Ford, “Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence,” Diabetes Care, vol. 28, no. 7, pp. 1769–1778, 2005. View at Publisher · View at Google Scholar
  26. C. Jericó, H. Knobel, M. Montero et al., “Metabolic syndrome among HIV-infected patients: prevalence, characteristics, and related factors,” Diabetes Care, vol. 28, no. 1, pp. 132–137, 2005. View at Publisher · View at Google Scholar
  27. K. Cianflone, C. Stanculescu, and R. Germinario, “Protease inhibitor effects on triglyceride synthesis and adipokine secretion in human omental and subcutaneous adipose tissue,” Antiviral Therapy, vol. 11, no. 6, pp. 681–691, 2006. View at Google Scholar
  28. R. Ross, “The pathogenesis of atherosclerosis: a perspective for the 1990s,” Nature, vol. 362, no. 6423, pp. 801–809, 1993. View at Publisher · View at Google Scholar · View at PubMed
  29. J. Danesh, P. Whincup, M. Walker et al., “Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses,” British Medical Journal, vol. 321, no. 7255, pp. 199–204, 2000. View at Google Scholar
  30. A. Lafeuillade, M. Sorice, T. Griggi, P. Pellegrino, M. Geoffroy, and N. Profizi, “Role of autoimmunity in protein S deficiency during HIV-1 infection,” Infection, vol. 22, no. 3, pp. 201–203, 1994. View at Publisher · View at Google Scholar
  31. K. L. Hassell, D. C. Kressin, A. Neumann, R. Ellison, and R. A. Marlar, “Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men,” Blood Coagulation and Fibrinolysis, vol. 5, no. 4, pp. 455–462, 1994. View at Google Scholar
  32. G. La Montagna, F. Cacciapuoti, R. Buono et al., “Insulin resistance is an independent risk factor for atherosclerosis in rheumatoid arthritis,” Diabetes and Vascular Disease Research, vol. 4, no. 2, pp. 130–135, 2007. View at Publisher · View at Google Scholar · View at PubMed