Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011, Article ID 919816, 5 pages
Clinical Study

Assessment of the Cardioankle Vascular Index in Pregnant Women Complicated with Hypertensive Disorders

1Department of Obstetrics and Gynecology, Nishisaitama-Chuo National Hospital, 2-1671 Wakasa, Tokorozawa, Saitama 359-1151, Japan
2Department of Obstetrics and Gynecology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan

Received 9 March 2011; Accepted 24 March 2011

Academic Editors: D. Chen, K. E. Clark, F. M. Reis, and G. Rizzo

Copyright © 2011 Atsushi Yoshida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


It was previously reported that the brachial-ankle pulse wave velocity (baPWV) is elevated in preeclamptic women. However, baPWV is strongly affected by blood pressure. Recently, a new index of vascular stiffness, the cardioankle vascular index (CAVI), was developed. CAVI is thought to be an index independent of blood pressure. We assessed CAVI in normotensive and hypertensive pregnant women. We studied a total of 109 Japanese women consisting of 23 nonpregnant healthy women (group A), 45 normotensive pregnant women (group B), 28 pregnant women complicated with established preeclampsia (group C), and 13 pregnant women with chronic hypertension (group D). The subject remained supine while the blood pressure, baPWV, and CAVI were recorded. No significant difference in baPWV was present between groups C and D, but the difference in CAVI was significantly high in group D. We believe that we can distinguish the vessel structural change between chronic hypertension and preeclampsia through simultaneous baPWV and CAVI measurements.