Figure 7: In vitro effect of FBPase and GS antisense cDNAs expressed in rat glioma-derived cell line. Invasiveness (a) was determined in semisolid medium by determining the number of foci that each cell can induce. Doubling time (b) of the various cells is determined using counting of viable cells. Value represents the mean of 8 experiments (corresponding to 3 sets of transfection) ± SEM. 𝑃 < 0.05, 𝑃 < 0.01 versus empty plasmid, and statistical analysis was made using Student test. Data adapted from Ardourel et al. [104].