Table of Contents
ISRN Organic Chemistry
Volume 2011, Article ID 948685, 4 pages
Research Article

Copper Perchlorate Hexahydrate: An Efficient Catalyst for the Green Synthesis of Polyhydroquinolines under Ultrasonication

1Department of Chemistry, Punjabi University, Patiala 147002, India
2Post Graduate Department of Chemistry, M.M. Modi College Patiala, Patiala 147001, India
3Department of Chemistry, Sant Longowal Institute of Engineering and Technology, Longowal 148106, India

Received 27 January 2011; Accepted 28 February 2011

Academic Editors: J. Drabowicz, P. M. T. Ferreira, and I. Tellitu

Copyright © 2011 Saurabh Puri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Copper perchlorate hexahydrate as an efficient catalyst was used for the synthesis of polyhydroquinolines by four-component condensation reaction of aldehyde, ethyl acetoacetate, dimedone, and ammonium acetate in excellent yields and short reaction times at room temperature under ultrasound irradiation. This novel synthetic method is especially favoured because it provides a synergy between copper perchlorate hexahydrate and ultrasound irradiation which offers the advantages of high yields, short reaction times, simplicity, and easy workup compared to the conventional methods reported in the literature.